XRPD & SAXS for Pharmaceutical Patents

Expert X‑ray technical analysis supporting patent applications and IP protection. Technical characterization and pattern comparison services for pharmaceutical companies and patent professionals.

Technical Analysis Services for Patent Applications

DANNALAB provides specialized X-ray characterization services supporting pharmaceutical patent applications. We offer technical expertise and analytical data that support IP protection strategies developed by your patent counsel.

Important: Our services provide technical analysis only, not legal advice or legal opinions. All legal and IP strategy decisions should be made in consultation with qualified patent attorneys. See important disclaimer below ↓

Confidentiality assured: All patent-related work conducted under strict NDA. We understand the sensitive nature of IP analysis and competitive intelligence.

Technical Data for Patent Applications — New Solid Forms or Formulations

We provide technical analysis to identify unique XRPD/SAXS physico-chemical properties that may be useful for patent specifications. (Patent strategy and claim drafting remain your patent attorney's responsibility.)

Unique Descriptor Identification

Technical identification of measurable X-ray descriptors that distinguish your form from prior art. Data provided to support your patent attorney's specification development.

Technical Parameter Support

Scientific expertise on XRPD/SAXS parameters suitable for patent specifications. Technical support for your patent attorney's claim drafting process.

Supporting Data Package

Complete analytical data with statistical uncertainties, suitable for patent office submissions as prepared by your patent counsel.

Note: We provide technical data and scientific expertise. Patent strategy, claim drafting, and legal decisions are made by your patent attorney. See disclaimer ↓

XRPD for Patent Analysis

Technical Analysis Supporting Freedom-to-Operate Studies

Technical data provided to support legal freedom-to-operate analysis conducted by your patent attorney. See disclaimer ↓

  • Digitize patent specifications — Extract peak positions, d-spacings, intensity ratios, and tolerances from patent claims, specifications, and images using dedicated software
  • Compare actual XRPD/SAXS measurements vs. patent claims — High-precision technical comparison of your measured pattern against patented specifications from both text and images using our dedicated analytical software
  • Technical evidence of differences — Comprehensive analytical study demonstrating technical differences (legal sufficiency determined by your patent counsel)
  • Quantitative statistical analysis — Statistical significance of pattern differences with uncertainty estimates

Technical Data for Patent Specifications

Analytical parameters for use by your patent attorney in developing patent specifications.

  • Unique peak signatures — Technical identification of characteristic peaks and their parameters
  • Unit cell parameters — Indexed patterns with crystallographic cell dimensions
  • Crystallinity descriptors — Amorphous fraction quantification
  • Peak intensity ratios — Characteristic intensity relationships

SAXS for Patent Claims

SAXS Parameters for Patent Specifications

Technical parameters that may be useful in patent specifications (as determined by your patent attorney).

  • Radius of gyration (Rg) — Size parameter for biologics and nanoparticles
  • Pair distance distribution P(r) — Shape descriptors and maximum dimensions
  • Bilayer thickness — For liposomes, LNPs, and vesicular systems
  • Lamellarity & structure type — Multi-lamellar vs. unilamellar, phase identification
  • Particle size distribution — Number- and volume-weighted distributions

Advantage: SAXS parameters are quantitative, reproducible, and well-defined — making them ideal for patent specifications that can be defended and enforced.

Materials & Medical Devices — Measurable Property Ranges

  • Quantify periodicities/d‑spacings — e.g., "d-spacing in the range of 5–6 nm"
  • Film thickness ranges — XRR-determined coating thickness specifications
  • Texture/crystallinity parameters — Preferred orientation, crystalline fraction
  • Proposed parameter windows for claims — Define acceptable ranges with supporting data

Applicable to transdermal patches, device coatings, bio-materials, and functional films.

Technical Analysis of Existing Patents

For existing patents containing XRPD and SAXS data, we provide technical analysis services. (Legal conclusions are made by your patent attorney.) See disclaimer ↓

Prior Art Technical Analysis

Technical analysis of X-ray data in prior art patents. Identification of technical differences or similarities. Legal interpretation provided by your patent counsel.

Technical Comparison Studies

Technical comparison of your product's X-ray data against patented specifications. Analytical evidence supporting freedom-to-operate analysis by your patent attorney.

Technical Evidence for Patent Challenges

Technical analysis providing analytical evidence that may support patent challenges. Legal strategy and proceedings conducted by your patent counsel.

Scientific Content Review

Expert technical review of accuracy and scientific validity of X-ray data in patent claims. Assessment of analytical methodology and data quality.

Data Digitization from Patent Images

Extraction and digitization of XRPD patterns and SAXS curves from patent images using dedicated software. Peak positions, d-spacings, and intensity ratios recovered from graphical data.

Pattern Comparison Software

Dedicated analytical software for high-precision technical comparison of measured patterns against patent specifications from both text claims and digitized images.

Comprehensive Patent Database

DANNALAB maintains a comprehensive database of digitized XRPD scans disclosed in pharmaceutical patents. Contact us if you need a patent figure converted to digital Excel format for technical analysis.

Patent analysis example

Example of patent XRPD data digitization and comparison

Technical Testing for IP Protection

If you suspect a competitor's product may relate to your intellectual property, we provide analytical testing and technical comparison. (Legal infringement determinations are made by your patent attorney based on our technical data.) See disclaimer ↓

We also provide analytical testing for product authentication and counterfeit detection.

Technical Evidence Collection

XRPD/SAXS testing of competitor products with technical comparison against your patent specifications.

Analytical documentation suitable for use by legal counsel in proceedings. We provide technical data, not legal conclusions.

Counterfeit Detection

Analytical method development for distinguishing authentic products from counterfeits using X-ray fingerprinting.

Non-destructive in-blister testing available (patented technology WO2024184529A1).

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Industrial Service for IP Professionals

Confidentiality

  • Your NDA accepted as-is
  • Secure handling of competitor samples
  • No disclosure to third parties

Fast Turnaround

  • Urgent: 48-72 hours available
  • Aligned with litigation deadlines
  • Committed delivery dates

Expert Technical Reports

  • Clear summaries of technical findings
  • Detailed technical appendices
  • Expert technical witness testimony available

Who We Serve

Pharmaceutical Companies

R&D teams developing new polymorphs, salts, co-crystals, or formulations. We provide technical characterization data supporting patent applications prepared by your patent counsel.

Generic Manufacturers

Technical comparison studies providing analytical data that supports freedom-to-operate analysis by your patent attorney before launching generic products.

Patent Attorneys & IP Lawyers

Technical analytical support for your patent prosecution, litigation, and opposition proceedings. We provide expert scientific data, you provide legal strategy.

Medical Device Companies

Technical characterization of device coatings, bio-materials, and functional films for patent applications.

Legal Teams

Expert technical witness services and analytical evidence for patent litigation. Technical testimony only, not legal opinions.

Business Development

Technical competitive intelligence based on X-ray characterization. Analytical data for IP landscape assessment by your legal team.

Confidential Technical Consultation

If you are an IP professional or a pharmaceutical scientist dealing with patents, please contact us to discuss technical analysis needs. All initial consultations are confidential.

We provide technical expertise. For legal advice on patent matters, please consult your patent attorney.

Contact for Patent Services

Important Information: Patent Analysis Services

Technical Analysis — Not Legal Advice

DANNALAB provides technical and scientific analysis of XRPD and SAXS data for patent-related applications. Our services constitute technical expertise only and do not constitute legal advice, legal opinions, or patent counsel.

What We Provide

  • Expert X-ray characterization and data analysis
  • Technical comparison of patterns vs. patent specifications
  • Quantitative analysis with statistical evaluation
  • Scientific interpretation of similarities/differences

What We Do NOT Provide

  • ✗ Legal advice or legal opinions
  • ✗ Freedom-to-operate legal conclusions
  • ✗ Patent validity assessments (legal)
  • ✗ Infringement determinations (legal)

Consult Patent Counsel: All patent-related legal decisions, including freedom-to-operate assessments, patent filing strategies, and infringement analyses, should be made in consultation with qualified patent attorneys or intellectual property counsel. DANNALAB is not a law firm and does not provide legal services.

Basis of Service: Our technical analysis is provided with professional care and best efforts, but without guarantee of specific outcomes, patent grants, or legal conclusions. Clients are solely responsible for all intellectual property and business decisions based on our technical reports.